Alphabetical listing of all products

A - B - C - D - E - F - G - H - I - J - K - L - M - N - O - P - Q - R - S - T - U - V - W - X - Y - Z

Prices
  • 25 mg - 60 EUR
  • 100 mg - 180 EUR
  • 250 mg - 360 EUR

ZSTK474

ZSTK474 is a new PI3K inhibitor with strong antitumor activity against human cancer xenografts without toxic effects in critical organs. Biochemical experiments confirmed ZSTK474 to be a potent pan-class I PI3K inhibitor (Ki values for alpha, beta, gamma, delta isoforms are 6.7 nM, 10.4 nM, 11.7 nM, and 1.8, nM respectively), with high selectivity over other classes of PI3K and protein kinases.

catalogue number: Z143
synonyms:
CAS: 475110-96-4
MW: 417.41 g/mol

References
J Natl Cancer Inst. 2006 Apr 19;98(8):545-56. PMID: 16622124
Acta Pharmacol Sin. 2010 Sep;31(9):1189-97. PMID: 20729870