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  • 25 mg - 22 EUR
  • 100 mg - 65 EUR
  • 250 mg - 130 EUR

Thalidomide

Thalidomide is a potent inhibitor of new blood vessel growth (angiogenesis) and is effective against several types of cancers. It intercalates into DNA in guanine-cytosine-rich regions, which affects the promoter regions of the genes that control the development of limbs, ears, and eyes, such as IGF-I and FGF-2. The subsequent loss of immature blood vessels is the primary cause of thalidomide-induced teratogenesis and may also be the mechanism of its anti-angiogenic activity.

catalogue number: T129
synonyms: Thalomid
CAS: 50-35-1
MW: 258.23 g/mol

References
Proc Natl Acad Sci U S A. 2009 May 26;106(21):8573-8. PMID: 19433787