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Trichostatin A

Trichostatin A is a specific inhibitor of the class I and II mammalian histone deacetylases (HDAC). It has been shown to cause the accumulation of acetylated histones with subsequent cell cycle arrest, terminal differentiation and/or apoptosis in various cancer cell lines, and to inhibit tumor growth in animals.

catalogue number: T077
synonyms: TSA
CAS: 58880-19-6
MW: 302.37 g/mol

References
J Biol Chem. 1990 Oct 5;265(28):17174-9. PMID: 2211619
J Biol Chem. 1993 Oct 25;268(30):22429-35. PMID: 8226751