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  • 25 mg - 43 EUR
  • 100 mg - 129 EUR
  • 250 mg - 258 EUR

Sunitinib malate

Sunitinib is a small molecule receptor tyrosine kinase inhibitor with direct antitumor as well as antiangiogenic activity. It targets the vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), KIT, and FLT3 receptor tyrosine kinases, and has Ki values of 9 and 8 nM for Flk-1 and PDGFR, respectively. Sunitinib has been approved for use in the treatment of kidney cancer, gastrointestinal stromal tumors and pancreatic neuroendocrine tumors.

catalogue number: S075
synonyms: Sutent, SU-11248
CAS: 341031-54-7
MW: 532.56 g/mol (malate)

References
J Med Chem. 2003 Mar 27;46(7):1116-9. PMID: 12646019
Clin Cancer Res. 2003 Jan;9(1):327-37. PMID: 12538485