Alphabetical listing of all products

A - B - C - D - E - F - G - H - I - J - K - L - M - N - O - P - Q - R - S - T - U - V - W - X - Y - Z

Prices
  • 5 mg - 85 EUR
  • 25 mg - 340 EUR
  • 100 mg - 1020 EUR

Sorafenib (tosylate)

Sorafenib is a biarylurea derivative that selectively targets several receptor tyrosine kinases and Raf kinases. It has IC50 values of 6, 22, 38 nM for Raf-1, wt BRAF and V599E mutant BRAF. It has been approved for use in the treatment of advanced renal cancer and hepatocellular carcinoma.

catalogue number: S073
synonyms: Nexavar, BAY 43-9006
CAS: 475207-59-1
MW: 637.03 g/mol (tosylate)

References
Cancer Res. 2004 Oct 1;64(19):7099-109. PMID: 15466206