Alphabetical listing of all products

A - B - C - D - E - F - G - H - I - J - K - L - M - N - O - P - Q - R - S - T - U - V - W - X - Y - Z

Prices
  • 5 mg - 41 EUR
  • 25 mg - 164 EUR
  • 100 mg - 492 EUR

(R/S)-roscovitine

Roscovitine is a highly efficient and selective inhibitor of certain cyclin-dependent kinases, including CDK2, CDK5, CDK7 and CDK9. It reversibly halts the cell cycle and DNA synthesis in several model systems and inhibits proliferation in various mammalian cell lines with an average IC50 of 16 microM.

catalogue number: R067
synonyms:
CAS: 186692-44-4
MW: 354.45 g/mol

References
J Med Chem. 1997 Feb 14;40(4):408-12. PMID: 9046330
Acc Chem Res. 2003 Jun;36(6):417-25. PMID: 15648953
Curr Opin Investig Drugs. 2004 Dec;5(12):1311-8. PMID: 15648953