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Prices
  • 5 mg - 52 EUR
  • 25 mg - 208 EUR
  • 100 mg - 624 EUR

Pictilisib

Pictilisib, formerly known as GDC-0941, is a potent, selective, orally bioavailable inhibitor of PI3K. It inhibits PI3K isoform p110alpha with a single digit nanomolar IC50 value. The compound exhibits in vitro antiproliferative properties with submicromolar potency in PTEN-negative cells and clear PI3K pathway modulation. It is currently being evaluated in human clinical trials for the treatment of cancer.

catalogue number: P139
synonyms: GDC-0941
CAS: 957054-30-7
MW: 513.64 g/mol

References
J Med Chem. 2008 Sep 25;51(18):5522-32. PMID: 18754654
Mol Cancer Ther. 2009 Jul;8(7):1725-38. PMID: 19584227