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  • 5 mg - 148 EUR
  • 25 mg - 592 EUR
  • 100 mg - 1776 EUR

Perifosine

Perifosine is an oral Akt (protein kinase B, PKB) inhibitor that is currently being tested in clinical trials. Unlike most kinase inhibitors, which target the adenosine triphosphate-binding region, perifosine targets the pleckstrin homology domain of Akt, thereby preventing its translocation to the plasma membrane. Perifosine exerts both Akt-dependent and Akt-independent effects.

catalogue number: P064
synonyms: KRX-0401, NSC 639966161, D-21266
CAS: 157716-52-4
MW: 461.66 g/mol

References
Eur J Cancer. 1997 Mar;33(3):442-6. PMID: 9155530
Mol Cancer Ther. 2003 Nov;2(11):1093-103. PMID: 14617782