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Prices
  • 5 mg - 52 EUR
  • 25 mg - 208 EUR
  • 100 mg - 624 EUR

Olaparib

Olaparib is a single digit nanomolar inhibitor of poly(adenosine diphosphate-ribose) polymerase (PARP), an enzyme that is involved in DNA damage repair. It exhibits IC50 values of 5 and 1 nM for PARP-1 and PARP-2, respectively, and is being developed as a drug for BRCA1- and BRCA2-defective cancers.

catalogue number: O057
synonyms: AZD2281, KU-0059436
CAS: 763113-22-0
MW: 434.46 g/mol

References
J Med Chem. 2008 Oct 23;51(20):6581-91. PMID: 18800822
Blood. 2010 Nov 25;116(22):4578-87. PMID: 20739657
Mol Cancer Ther. 2011 Oct;10(10):1949-58. PMID: 21825006