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Mitomycin C

Mitomicin C is a natural product isolated from Streptomyces caespitosus or Streptomyces lavendulae. It is a potent DNA crosslinker with high efficiency and absolute specificity for the sequence CpG. Its binding to DNA causes DNA damage and induces cell death. It produces oxygen radicals and is preferentially toxic to hypoxic cells.

catalogue number: M127
synonyms: Mitomycin, Mutamycin
CAS: 50-07-7
MW: 334.33 g/mol

References
Chem Biol. 1995 Sep;2(9):575-9. PMID: 9383461