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  • 25 mg - 28 EUR
  • 100 mg - 85 EUR
  • 250 mg - 170 EUR

6-mercaptopurine

6-mercaptopurine is widely used to treat malignancies, rheumatic diseases, dermatologic conditions, inflammatory bowel disease, and solid organ transplant rejection. However, thiopurine drugs have a relatively narrow therapeutic index and can exhibit life-threatening toxicity, often due to myelosuppression. Mercaptopurine inhibits purine nucleotide synthesis and metabolism, altering the synthesis and functioning of RNA and DNA.

catalogue number: M126
synonyms: Mercaptopurine, Purinethol
CAS: 50-44-2
MW: 152.18 g/mol

References
Eur J Clin Pharmacol. 2008 Aug;64(8):753-67. PMID: 18506437
Aliment Pharmacol Ther. 2006 Sep 1;24(5):715-29. PMID: 16918876