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  • 5 mg - 98 EUR
  • 25 mg - 392 EUR
  • 100 mg - 1176 EUR

Myoseverin

Myoseverin is a 2,6,9-trisubstituted purine derivative that binds to tubulin and prevents its polymerization. It was discovered in a morphological differentiation screen and induces the reversible fission of multinucleated myotubes into mononucleated fragments. In cancer cells, myoseverin leads to mitotic arrest with subsequent cell death.

catalogue number: M053
synonyms:
CAS: 267402-71-1
MW: 432.52 g/mol

References
Nat Biotechnol. 2000 Mar;18(3):304-8. PMID: 10700146
J Med Chem. 2001 Dec 20;44(26):4497-500. PMID: 11741468
Eur J Med Chem. 2006 Dec;41(12):1405-11. PMID: 16996651