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  • 5 mg - 194 EUR
  • 25 mg - 776 EUR
  • 100 mg - 2328 EUR

MLN8054

MLN8054 is an orally bioavailable, potent and selective inhibitor of the protein kinase Aurora A. MLN8054 inhibits AURKA activity with an IC50 of 4 nM (its IC50 for AURKB is 170 nM). MLN8054 treatment results in G2/M cell cycle arrest, spindle defects and cell death in many tumor cell lines.

catalogue number: M051
synonyms:
CAS: 869363-13-3
MW: 476.85 g/mol

References
Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4106-11. PMID: 17360485
Mol Cell Biol. 2007 Jun;27(12):4513-25. PMID: 17438137