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  • 5 mg - 194 EUR
  • 25 mg - 776 EUR
  • 100 mg - 2328 EUR

Ixazomib (syn. MLN-2238)

Ixazomib is a potent, reversible, and specific inhibitor of the 20S proteasome with an IC50 value of 3.4 nM. It is active in preclinical models of lymphoma and lymphoma that are refractory to bortezomib treatment. In therapeutic applications, it is delivered as a prodrug (MLN-9708), which is orally bioavailable and is rapidly hydrolyzed to yield the bioactive species Ixazomib.

catalogue number: M050
synonyms: MLN-2238
CAS: 1072833-77-2
MW: 361.03 g/mol

References
Clin Cancer Res. 2011 Aug 15;17(16):5311-21 PMID: 21724551