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MG-132

MG-132 is a specific, potent, reversible and cell-permeable proteasome inhibitor with a Ki value of 4 nM. It reduces the degradation of polyubiquitinylated proteins in mammalian cells by blocking the 26S complex.

catalogue number: M049
synonyms: MG132, N-(benzyloxycarbonyl)leucinylleucinylleucinal
CAS: 133407-82-6
MW: 475.62 g/mol

References
J Biochem. 1996 Mar;119(3):572-6. PMID: 8830056
Anticancer Res. 2001 Nov-Dec;21(6A):3941-7. PMID: 11911275