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  • 5 mg - 220 EUR
  • 25 mg - 880 EUR
  • 100 mg - 2640 EUR

Lestaurtinib

Lestaurtinib is a multi targeted tyrosine kinase inhibitor. In preclinical studies, it was shown to inhibit FLT3 at nanomolar concentrations, prompting its rapid development as a potential agent for treating AML. Phase I studies have shown it to be an active agent, particularly when used in combination with cytotoxic drugs. It is currently undergoing Phase II and Phase III studies in patients with FLT3-ITD AML.

catalogue number: L100
synonyms: CEP-701, KT-5555
CAS: 111358-88-4
MW: 439.46 g/mol

References
Cancer Res. 1999 May 15;59(10):2395-401. PMID: 10344749
Expert Opin Investig Drugs. 2010 Mar;19(3):427-36. PMID: 20141349