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Lapatinib ditosylate

Lapatinib is an orally available small molecule that targets the tyrosine activity of the erbB1 and erbB2 (Her2) receptors. It is used to treat breast cancers and other solid tumours.

catalogue number: L047
synonyms: Tykerb, GW-572016
CAS: 388082-78-8
MW: 925.46 g/mol (ditosylate)

References
Oncogene. 2002 Sep 12;21(41):6255-63. PMID: 12214266
Cancer Res. 2004 Sep 15;64(18):6652-9. PMID: 15374980
EGFR kinase domain complexed with GW572016 PDB: 1XKK