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K252a

K252a is an alkaloid related to staurosporin, but isolated from Nocardiopisis sp. soil fungi. It is potent inhibitor of multiple serine/threonine protein kinases (IC50s of 10 to 30 nM), including Ca2+/calmodulin-dependent protein kinase II, protein kinase A, protein kinase C and protein kinase G.

catalogue number: K145
synonyms:
CAS: 99533-80-9
MW: 467.47 g/mol

References
Biochem Biophys Res Commun. 1990 Aug 31;171(1):148-54. PMID: 2393389
Biochem Biophys Res Commun. 1991 Nov 27;181(1):423-9. PMID: 1659814