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  • 5 mg - 121 EUR
  • 25 mg - 484 EUR
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KU0063794

KU0063794 is selective inhibitor of mammalian target of rapamycin (mTOR) with an IC50 value of 10 nM. It displays no activity against PI3-kinase or 76 other kinases tested. It inhibits the activation of Akt, S6K and SGK, but not RSK. Treatment of cells suppresses their growth and induces G1 cell cycle arrest in vitro.

catalogue number: K046
synonyms: KU-0063794
CAS: 938440-64-3
MW: 465.54 g/mol

References
Biochem J. 2009 Jun 12;421(1):29-42. PMID: 19402821