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  • 5 mg - 230 EUR
  • 25 mg - 920 EUR
  • 100 mg - 2760 EUR

JNJ-26481585

JNJ-26481585 is a hydroxamic acid derivative and a second-generation pan-HDAC inhibitor that has demonstrated high potency in preclinical studies. Cells treated with this compound accumulate highly acetylated histones, which may induce chromatin remodeling, inhibit the transcription of tumor suppressor genes, inhibit tumor cell division, and induce apoptosis in tumor cells.

catalogue number: J044
synonyms: Quisinostat
CAS: 875320-29-9
MW: 394.48 g/mol

References
Leukemia. 2009 Oct;23(10):1894-903. PMID: 19494837
Leuk Res. 2010 Feb;34(2):221-8. PMID: 19682743