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Indirubin-3'-monooxime

Indirubin-3'-monooxime is an inhibitor of GSK3b (IC50=22 nM), CDK1 (IC50=180 nM) and CDK5 (IC50=100 nM). Treatment with indirubin-3-monooxime caused time-dependent inhibition of cell growth, with the treated cells exhibiting many hallmark features of apoptosis.

catalogue number: I042
synonyms:
CAS: 160807-49-8
MW: 277.3 g/mol

References
Biomed Pharmacother. 2009 Feb;63(2):146-54. PMID: 18450412