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  • 5 mg - 52 EUR
  • 25 mg - 208 EUR
  • 100 mg - 624 EUR

Hydroxyurea

Hydroxyurea is a drug that inhibits DNA synthesis by inhibiting ribonucleoside diphosphate reductase. The entire replicase complex, including ribonucleotide reductase, is inactivated and DNA synthesis is selectively inhibited, causing cell death in S phase and synchronizing the surviving cells. It is used in the clinic to treat myeloproliferative diseases, sickle-cell disease, AIDS, and psoriasis.

catalogue number: H083
synonyms: HU, Cytodrox, Hydrea, Biosupressin, Hydroxycarbamide
CAS: 127-07-1
MW: 76.05 g/mol

References
Semin Oncol. 1992 Jun;19(3 Suppl 9):1-10. PMID: 1641648