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Gö 6976

Gö 6976 inhibits the Ca(2+)-dependent isozymespf protein kinase C (PKC) alpha and beta 1 at nanomolar concentrations. Kinetic analysis revealed that PKC inhibition by Gö 6976 is competitive with respect to ATP, non-competitive with respect to the protein substrate, and mixed type with respect to phosphatidylserine.

catalogue number: G140
synonyms: PD 406976, Go 6976
CAS: 136194-77-9
MW: 378.43 g/mol

References
J Biol Chem. 1993 May 5;268(13):9194-7. PMID: 8486620
Proc Natl Acad Sci U S A. 1993 May 15;90(10):4674-8. PMID: 7685108