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  • 5 mg - 62 EUR
  • 25 mg - 248 EUR
  • 100 mg - 744 EUR

Enzastaurin

Enzastaurin is an inhibitor of several isoforms of protein kinase C, including beta, alpha, gamma and epsilon, with IC50 values of 6, 39, 83 and 110 nM, respectively. Enzastaurin inhibits tumor growth through several mechanisms: block of tumor cell proliferation, induction of tumor cell apoptosis and inhibition of tumor-induced angiogenesis.

catalogue number: E136
synonyms: LY-317615
CAS: 170364-57-5
MW: 515.61 g/mol

References
Cancer Res. 2005 Aug 15;65(16):7462-9. PMID: 16103100
Expert Opin Investig Drugs. 2008 Jun;17(6):939-44 PMID: 18491994