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  • 5 mg - 52 EUR
  • 25 mg - 208 EUR
  • 100 mg - 624 EUR

Docetaxel

Docetaxel is a semi-synthetic taxane used clinically for the treatment of breast, ovarian, and non-small cell lung cancer. It binds to tubulin and stabilizes the microtubular cytoskeleton, thereby inhibiting microtubule dynamics. This causes cell cycle arrest during mitosis and subsequent cell death. The mean IC50 for docetaxel observed on the NCI60 panel was 23 nM.

catalogue number: D028
synonyms: Taxotere
CAS: 114977-28-5
MW: 807.88 g/mol

References
Semin Oncol. 1995 Apr;22(2 Suppl 4):3-16. PMID: 7740328
J Natl Cancer Inst. 1995 May 3;87(9):676-81. PMID: 7752272