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Cyclophosphamide

Cyclophosphamide is a nitrogen mustard alkylating agent belonging to the oxazophorine class. It binds to N7 of guanine in DNA, on the imidazole ring, and forms both interstrand and intrastrand crosslinkages. Cyclophosphamide is used to treat various types of cancer and some autoimmune disorders.

catalogue number: C120
synonyms: Clafen, Endoxan, Cytoxan, Neosar, Procytox, Cytophosphane
CAS: 50-18-0
MW: 261.09 g/mol

References
Mutat Res. 1994 Dec;318(3):205-26. PMID: 7527485
Curr Pharm Des. 1999 Aug;5(8):555-60. PMID: 10469891