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  • 5 mg - 140 EUR
  • 25 mg - 560 EUR
  • 100 mg - 1680 EUR

Cabozantinib

Cabozantinib is a small molecule kinase inhibitor of MET and VEGFR2, as well as a number of other receptor tyrosine kinases that have also been implicated in tumor pathobiology, including RET, KIT, AXL. Treatment with cabozantinib inhibited MET and VEGFR2 phosphorylation and led to significant reductions in cell invasion.

catalogue number: C090
synonyms: XL184
CAS: 849217-68-1
MW: 501.51 g/mol

References
Expert Opin Investig Drugs. 2011 Mar;20(3):407-413. PMID: 21314233
Mol Cancer Ther. 2011 Sep 16. PMID: 21926191