Alphabetical listing of all products

A - B - C - D - E - F - G - H - I - J - K - L - M - N - O - P - Q - R - S - T - U - V - W - X - Y - Z

Prices
  • 5 mg - 74 EUR
  • 25 mg - 296 EUR
  • 100 mg - 888 EUR

CAL-101 (Idelalisib)

CAL-101 is a potent inhibitor of PI3 kinase with an IC50 of 65 nM for the p110d isoform. It blocks constitutive PI3K signaling, which disfavours Akt phosphorylation and promotes apoptosis in primary CLL cells ex vivo in a dose- and time-dependent fashion.

catalogue number: C020
synonyms: GS-1101, Idelalisib
CAS: 870281-82-6
MW: 415.42 g/mol

References
Blood. 2010 Sep 23;116(12):2078-88. PMID: 20522708