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  • 5 mg - 41 EUR
  • 25 mg - 164 EUR
  • 100 mg - 492 EUR

Bohemine

The 2,6,9-trisubstituted purine derivative bohemine is a synthetic inhibitor of cyclin-dependent kinases that was developed from the original hit olomoucine. Bohemine inhibits CDK1 and CDK2 with IC50 values of around 1 microM. It also exhibits antitumour activity in vitro, with a mean IC50 value of 27 microM.

catalogue number: B018
synonyms:
CAS: 189232-42-6
MW: 340.43 g/mol

References
Electrophoresis. 2000 Nov;21(17):3757-64. PMID: 11271495
Technol Cancer Res Treat. 2002 Aug;1(4):247-56. PMID: 12625783
Clin Cancer Res. 2005 Jul 1;11(13):4875-87. PMID: 16000586