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  • 5 mg - 60 EUR
  • 25 mg - 240 EUR
  • 100 mg - 720 EUR

Adriamycin

Adriamycin is an anthracycline antibiotik that intercalates into DNA and causes DNA damage. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas. It inhibits the progression of the enzyme topoisomerase II by stabilizing the complex formed after the enzyme has broken the DNA chain during replication. This prevents the resealing of the double helix and thereby halts replication.

catalogue number: A009
synonyms: Doxorubicin, Rubex, NSC-123127
CAS: 25316-40-9
MW: 579.98 g/mol

References
Cancer Chemother Rep. 1969 Feb;53(1):33-7. PMID: 5772652
Biochimie. 1984 May;66(5):333-52. PMID: 6380596