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  • 25 mg - 85 EUR
  • 100 mg - 255 EUR
  • 250 mg - 510 EUR

17-AAG

17-AAG (17-N-Allylamino-17-demethoxygeldanamycin) is a derivative of the antibiotic geldanamycin that is being tested in the treatment of cancer. 17-AAG exerts its effect by inhibiting the ATPase activity of the heat shock protein HSP90, resulting in degradation of HSP90 client proteins via the ubiquitin proteosome pathway.

catalogue number: A001
synonyms: Tanespimycin, NSC330507, CP 127374
CAS: 75747-14-7
MW: 585.69 g/mol

References
Future Oncol. 2005 Apr;1(2):273-81. PMID: 16555999
Curr Mol Med. 2009 Jun;9(5):654-64. PMID: 19601813